This quantity commemorates the fiftieth anniversary of the looks in quantity four in 1948 of Dr. Jeffries Wyman's well-known paper during which he "laid down" the principles of linkage thermodynamics. specialists during this sector give a contribution articles at the cutting-edge of this significant box and on new advancements of the unique thought. one of the issues coated during this quantity are electrostatic contributions to molecular unfastened energies in answer; site-specific research of mutational results in proteins; allosteric transitions of the acetylcholine receptor; and decoding the molecular code of hemoglobin allostery.
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